李善德的老婆在原著中没有名字，就叫“李夫人”，剧版出场就直接领便当。在电影里她叫做郑玉婷（杨幂饰演），还给加了“严妻”的人设，给了很多戏份，相比原著，让这个人物的形象更加丰满，也给故事添加了不少温情戏码。
李善德在广州收留的奴隶林邑奴（刘俊谦饰演），是岭南经略府掌书记赵欣宁（孙阳饰演）安插在李善德身边的卧底。原著中岭南经略使何履光（林雪饰演）派出刺客追杀李善德，林邑奴为了给他报信翻山越岭，最终疲累“炸肺”而死。
电影中则给林邑奴加了很多戏份，让他成为李善德身边的得力助手，也给力他更加高光的表现。最后林邑奴为救李善德，死于宦官鱼朝恩（常远饰演）派出的刺客刀下，比原著中的“死法”更加壮烈。
也许是马伯庸不擅长写“武侠”，《长安的荔枝》原著是比较“温和”的小说，并没有着力描写“武打”的段落。何履光派刺客追杀李善德，那些刺客最后也并没有遇到李善德，而是在山中遭遇猛虎而被团灭。
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