New Study Shows Type Specific IgG Blood Test is FALSE NEGATIVE 12-30% of the time
Published in the most recent edition of the journal Sexually Transmitted Infections:
False-negative type-specific glycoprotein G antibody responses in STI clinic patients with recurrent HSV-1 or HSV-2 DNA positive genital herpes
http://sti.bmj.com/content/early/2016/01/11/sextrans-2015-052213.abstract
Quote
Conclusions: Commercial type-specific gG HSV-1 or HSV-2 antibody assays were false negative in 12–30% of patients with recurrent HSV-1 or HSV-2 DNA positive genital lesions. The clinical and epidemiological use of type-specific HSV serology can be hampered by false-negative results, especially if based on a single test.