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国外用于临床试验或即将上市的10个新药的新闻
The acyclovir family of herpes antivirals has been around in one form or another for the last 20 years. It's high time some progress was made, especially given that the ASHA says 50% of women in the USA will have genital herpes by 2025.
在过去20年中，Acyclovir（无环鸟苷）系列药物成为疱疹抗病毒治疗的最普遍，最主要的办法（这里的最主要含有唯一的成份，是一种无奈的情绪）。这是一个急需要改变的状况了，特别是ASHA预测，在2025年，百分之50的美国女性将患有生殖器疱疹疾病。
Here is a shortlist of the most likely new treatments to become available soon, in order of how close they are to market, number 1 being the closest to market. Make your own additions to, or comments on, the list.
这里列出即将问世的全新的治疗方式，根据最有可能上市的次序，就是说列在第一号的产品最可能率先上市。你可以为我作补充，或者发表自己的看法。
Here's the countdown:
1. Herpevac
Although there's a mysterious quiet at GSK recently, Herpevac is apparently finishing up Phase III trials. It won't be of any use to anyone who already has herpes, but it's the first real attempt to bring a vaccine to market. Rumor has it that the vaccine is around 75% effective in women who don't already carry either herpes type.
尽管GSK公司对他们的新药Herpevac一直保持低调，但已经可以确定该药品已经完成了第三阶段的审批测试。该种药物不是用于已患上疱疹的病人，而是将一种疱疹疫苗推向市场。根据非官方透露，该种疫苗可以帮助女性对两种疱疹病毒有75%的防御作用。
2. Nanobio NB-001
Ok, so it's a cream, but it's no ordinary cream. Nanobio's NB-001 uses extremely small particles called nanodroplets, which penetrate the skin and attack the virus directly. It makes Zovirax look antiquated.
是的，这是一种乳霜，但它非同一般。Nanobio’s NB-001乳霜含有极其微小颗粒，被称作Nanodroplets，它可以直接渗透人体肌肤杀灭病毒。它可以看作是Zovirax的新型替代产品。
3. Starpharma Vivagel
A new condom-coating that might also come as a cream. Recent trials on animals have shown it is between 85 and 100 per cent effective at blocking HIV and Herpes transmission.
Starphrma Vivagel是一种新型的乳膏用于涂抹在避孕套上，经过对动物的试验，它对HIV阻挡率达到85%，对疱疹病毒阻挡率几乎是100%。
4. Astellas ASP-2151
The most promising of the long-awaited Helicase Primase Inhibitors (HPI) drugs. And I really mean long-awaited. This is like super-acyclovir, and there's been some speculation that it could inhibit the virus so effectively that asymptomatic shedding may not be an issue.
Astellas ASP-2151这是最有希望，期待已久的HPI（解螺旋酶抑制剂）药物。是的，我的意思是非常期待，因为概要可以看作是超级的无环鸟苷，据推测它可以极为有效的控制病毒，并不会带来任何的临床反应。
5. Immunovex HSV2
A genetically-modified live herpes virus that won't be able to cause any symptoms, but will guard against infection from the symptomatic type. Immunovex plan to hold Phase I trials this year. The theory behind the vaccine is solid, and the animal trials were successful.
通过转基因手段是疱疹病毒无法在体内爆发，但还是要控制和防止病毒的传染。Immunovex计划在今年第一阶段的测试。据说相关的疫苗已经研制成功，并已近通过动物测试。
6. ACAM-529
Harvard's modified herpes virus can't multiply or infect cells. Two important genes are deleted to take the bite out of herpes. Scientists hope that this vaccine will prepare the body should it be attacked by the real virus. It may also help symptomatic people already carrying herpes. Acambis are investigating the technology, and Harvard continues to research the treatment. You can donate to their research here.
哈佛研制ACAM-529可以改良疱疹病毒，使它无法快速繁殖或入侵细胞。将疱疹病毒中两个重要的基因去除。科学家希望这种药物可以帮助人体抵抗病毒入侵，对已患上疱疹疾病的患者也可以提供一定程度的帮组。该药物仍在进一步研制过程中，你可以通过捐赠为他们提供帮助。
7. University of Florida vaccine
This is pretty much the Holy Grail of herpes vaccines, with the potential to actually cure people of the virus. The University proposes a vaccine that actually cuts into the structure of the virus, damaging it so significantly that it is eaten up by the body.
该药物可以看做是疱疹患者的圣杯，因为它是确实针对人体中的病毒而研发的。佛罗里达大学研究者表示该疫苗可以破坏病毒的内部架构，真正的将病毒杀死于体内。
