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BNT163 疱疹疫苗试验阶段开始2个月了 [复制链接]

1#

2024年8月更新:

如果您同意加入此研究,您需要完成以下研究程序:


  • 接受两剂研究疫苗(BNT163),并完成注射日记
  • 医疗信息审核
  • 接受包括但不限于心电图(ECG)、体格检查、尿检、生殖器拭子检查等检查
  • 进行血液测试以确认您的健康状况
  • 接受基因检测
  • 在整个研究期间采集血液样本

该研究共包括11次访问,历时约67周(1.2年),但如果出于安全考虑,可能需要额外访问。

请注意,该研究要求您亲自前往位于费城的宾夕法尼亚大学佩雷尔曼高级医学中心进行临床访问。

如果您符合以下条件,您可能有资格参与此研究:

条件:健康、志愿者、有疱疹病史
年龄:18至55岁
性别:不限

参加此试验的具体要求如下:


  • 体重指数(BMI)在18.5 kg/m²至35 kg/m²之间,且初次访问时体重至少50公斤
  • 愿意并能够遵守预定的访问安排、治疗时间表和实验室检查
  • 在研究人员根据您的病史、体格检查、12导联心电图、生命体征和筛查实验室检测(血液临床实验室)的临床判断下,整体健康状况良好
  • 过去的医疗记录中已确诊有由疱疹引起的复发性生殖器病变
  • 愿意在整个研究期间停止抑制治疗,大多数研究期间允许进行发作性治疗
  • 不可怀孕或哺乳
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2#

这个是特效药吗,怎么感觉招的是患者,跟疫苗的概念都不一样
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3#

是疫苗。好像和其他的确实不一样,一般是没有得过的人注射疫苗。
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4#

回复 3楼学会爱自己的帖子

所以很奇怪,有点像特效药
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5#

Are there any herpes (HSV) vaccines currently being studied?
Yes, vaccines are currently being researched to target both HSV-1 and HSV-2. Most are being developed for HSV-2. But since the viruses are so similar, an HSV-2 vaccine would also likely work to prevent or treat HSV-1, too.

There are two types of HSV vaccines being studied:

Treatment vaccines: These vaccines would benefit people who’ve already been infected with HSV. They could improve symptoms, help blisters heal faster, and lower the risk of spreading the virus to other people.
Preventative vaccines: These vaccines would benefit people who haven’t been exposed to HSV. They would train your immune system to prevent an HSV infection if you were exposed to the virus in the future.
Just as with any vaccine, all HSV vaccines will need to go through three types of clinical trials — phase 1, 2, and 3 trials — before being approved by the FDA. This to make sure that they’re safe and effective for humans. This process typically takes several years. So, it will likely be some time before we see an HSV vaccine come to market. Here are a few HSV vaccine candidates being studied right now.
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6#

上面这段话回复了。是两种不同类型疫苗。一个是对没有得过的。另外一种是已经感染的(可以降低症状并且防止感染其他人)
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