世界卫生组织报告：全球５亿人感染HSV-2生殖器疱疹病毒
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世界卫生组织（WHO）于2008年10月1日发布了全球首份HSV-2生殖器疱疹感染报告，新华社随后报道过，但由于报道得过于缩水，本人按照medicinenet的英文报道重新翻译整理并且加了一些注释。
世界卫生组织（WHO）发布首份全球HSV-2生殖器疱疹感染报告
By Miranda Hitti
WebMD Health News
评论：Louise Chang, MD
【空想者编译】
首发于生殖器疱疹战友吧
http://www.paozhen8.com2008年10月1日发布
全球有超过5亿人感染单纯疱疹病毒二型（HSV-2），该病毒主要引起生殖器疱疹症状，每年新增感染病例近2千4百万例。
此数据是依照全球首个单纯疱疹病毒二型（HSV-2）流行病学调查（病例总和）以及单纯疱疹病毒二型（HSV-2）的感染范围（新增感染病例）统计得出的结果。
以下为世界卫生组织公布的基于2003年全球调查研究的大体内容：
全球有5亿3千6百万年龄在15至49岁的人群感染单纯疱疹病毒二型（HSV-2），占这个年龄段人口的16％，每年此年龄段的人口中新增2千3百6十万感染病例。【空想者注：每年新增病例数量仅为2003年一年的统计结果】
要注意的两点是：此评估仅统计了15至49岁年龄段的人群；调查数据来自2003年。单纯疱疹病毒一型（HSV-1）也能引起生殖器疱疹，但是HSV-1主要感染口唇，而HSV-2主要感染生殖器。HSV-2主要通过性行为传播，亦可能在分娩时由母体传染给婴儿。【空想者注：欲了解如何避免传染新生儿HSV-2的相关内容，请查阅本论坛“HSV与怀孕”专题】
伦敦皇家学院和世界卫生组织的研究表明，绝大部分HSV-2患者不知道自己感染了HSV-2，并且没有任何症状。
从全球范围观察得出，女性的HSV-2感染率高于男性，并且呈现地区流行率多样性：欧洲西部的男性HSV-2流行率最低，为13％；而在撒哈拉以南的非洲地区，女性HSV-2流行率最高，70％的女性感染了HSV-2。
研究者同时声明，他们发布的报告“不应当被视为权威结论”，因为全球一些地区并没有进行HSV-2流行病学调查，无法得到切实数据。【空想者注：当然包括中国】
来源：Looker, K. Bulletinof the World Health Organization, October 2008; vol 86: pp 737-816.
WebMD Medical Reference: "Genital Herpes Glossary of Terms." News release, World Health Organization.
后记：
世界卫生组织（WHO）于2008年10月1日发布了全球首份HSV-2生殖器疱疹感染报告，其公布的调查结果连我都大吃一惊，有超过5亿人感染HSV-2，并且大家要注意几点：1，这个报告只统计了15至49岁的人群感染率；2，调查数据来自2003年；3，因为HerpeSelect等型特异性血清检测试剂未在中国大陆普及，所以这份报告没有包括中国、东南亚等国家和地区的数据（就算有，也仅仅只是局部课题的零星数据）；4，根据报告，全球最低的感染率为西欧男性，但即使最低也达到了13％，中国如此庞大的人口，再加上众所周知的目前中国对性的开放程度，结果可想而知。
综合这几点大家想想，如果将年龄段放宽、把2003年到2008年5年的新增感染病例算进去、再把中国等国家和地区算进去的话，实际数据最保守最起码都超过7亿人口了！7亿是个什么概念？全球60亿人口，也就是说，平均8至9个人中就有一个HSV-2感染者，九分之一的比例，并且，感染人数在持续猛增！
所以，兄弟姐妹们啊！还能说什么呢？除了流感全部亚型、HPV全部亚型、疱疹病毒家族的其他亚型外，我实在找不出比HSV-2更普遍的人群病毒感染了！就连成天充斥耳目的肝炎病毒HBV，全球流行病学调查也只有5％的人群感染率。糖尿病的全球发病率为3％－5％、心脑血管疾病的全球平均发病率为0.6％，然而在日常生活中我们发现早就对某人因高血压而住院治疗的消息习以为常了。所以，站在了解HSV-2的角度来看，我真的想问这个病毒算什么？它不致命、不遗传，除了偶尔在生殖器区域折腾几个痘痘外对机体健康产生不了任何影响，事实上全人类基本都已经成为了疱疹家族的宿主，面对如此庞大的人群感染，人们照样若无其事地向前发展，就是因为HSV-2是一个全世界普遍存在的轻微皮肤感染，仅此而已。
作为论坛版主，真心希望大家能够打起精神来，正视HSV-2，然后忽视HSV-2！HSV-2是我们充斥着喜怒哀乐的人生组成，勇敢地跨过这道小坎，人生要有经历才能成长，我希望看到的是，大家因为HSV-2开始关注自己的身体、开始明白自己需要承担的责任、开始更加努力地创造属于自己的辉煌人生！
原文：
Half a Billion Have Genital Herpes Virus
World Health Organization Publishes First Global Estimates of Herpes Simplex Virus Type 2 Infection
By Miranda Hitti
WebMD Health News
Reviewed By Louise Chang, MD
Oct. 1, 2008 -- More than half a billion people are infected with the herpes simplex virus type 2, the virus that causes most cases of genital herpes, and nearly 24 million new cases happen per year.
That's according to the first global estimate of the prevalence (total number of cases) and incidence (number of new cases) of herpes simplex virus type 2 (HSV-2) infection.
Here are the estimates, published in the Bulletin of the World Health Organization and based on studies from around the world published in 2003:
536 million people aged 15-49 are infected with herpes simplex type 2 virus. That's 16% of people in that age range.
Every year, 23.6 million people aged 15-49 become infected with the herpes simplex type 2 virus.
The estimates only focus on HSV-2 among people aged 15-49; data came from studies published in 2003. Genital herpes can also be caused by herpes simplex virus type 1 (HSV-1), but HSV-1 typically infects the mouth and HSV-2 typically infects the genitals. HSV-2 is usually spread through sex; it can also pass from mother to child during birth.
Most people with herpes simplex virus type 2 don't know they're infected and don't have symptoms, note the researchers, who work at Imperial College London and the World Health Organization (WHO).
HSV-2 prevalence was higher among women than men and varied across world regions. Western European men had the lowest prevalence rate (13%) and women in sub-Saharan Africa had the highest prevalence rate (70%).
The researchers caution that their estimates "should not be taken as being definitive," partly because some world regions had few HSV-2 studies to analyze.
SOURCES: Looker, K. Bulletinof the World Health Organization, October 2008; vol 86: pp 737-816. WebMD Medical Reference: "Genital Herpes Glossary of Terms." News release, World Health Organization.
2008 WebMD, LLC. All Rights Reserved.
原文网址：
http://www.medicinenet.com/script/main/art.asp?articlekey=93133WHO原文：
An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection
Katharine J Looker, Geoffrey P Garnett, George P Schmid
ObjectiveTo estimate the global prevalence and incidence of herpes simplex virus type 2 (HSV-2) infection in 2003.
Methods：A systematic review was undertaken of published seroprevalence surveys describing the prevalence or incidence of HSV-2 by age and gender. For each of 12 regions, pooled prevalence values by age and gender were generated in a random-effect model. HSV-2 incidence was then estimated from these pooled values using a constant-incidence model. Values of the HSV-2 seroprevalence from the model fits were applied to the total population to estimate the numbers of people infected.
Findings：The total number of people aged 15–49 years who were living with HSV-2 infection worldwide in 2003 is estimated to be 536 million, while the total number of people who were newly infected with HSV-2 in 2003 is estimated to be 23.6 million. While the estimates are limited by poor availability of data, general trends are evident. For example, more women than men were infected, and the number infected increased with age. Although prevalence varied substantially by region, predicted prevalence was mostly higher in developing regions than developed regions.
Conclusion：The prevalence of HSV-2 is relatively easy to measure since infection is lifelong and has a specific serological test. The burden of disease is less easy to quantify. Despite the often sparse data on which these estimates are based, it is clear that HSV-2 infection is widespread. The dramatic differences in prevalence between regions are worthy of further exploration.
原文网址：
http://www.who.int/bulletin/volumes/86/10/07-046128-ab/en/index.html请尊重作者和翻译者劳动,转载者尊重自己的道德,注明作者和出处: 空想者
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