这是在IHA(国际疱疹协会)上查到的多媒体资料,这个动画短片形象的演示了生殖器疱疹病毒感染,传播
过程及药物抑制原理,看这些动画前需要安装QuickTime播放器,因附件比较大传不上来,只有请大家进入原文地址去看动画了,原文描述我简单翻译了一下(可能不太专业),希望对战友们有所帮助。
原文地址(不过要先注册才能登陆):
http://www.herpesalliance.org/press_members/image_bankanimation.htmHerpes Animations(疱疹演示动画)The following 3-D animation gives you a unique virus 'eye' view of the processes of genital
herpes infection, transmission to sexual partner, and how antiviral drugs disrupt these
processes to treat symptoms and reduce transmission.
这个3D动画给你一个独特的视觉了解生殖器疱疹如何感染,传染到性伴侣的过程,以及抗病毒药物是怎样
破坏感染传播链来治疗和减少传染的。
Click on the following to view and download animation clips, the full animation (82 secs) or selected stills.
点击如下内容可观看和下载动画短片,其中有分段介绍的短片,也有串联起来完整的动画演示(共82秒)。
Guide to clips(片段向导):1&2: Initial infection (40 secs)初次感染(40秒)
3: Latent infection & reactivation (20 secs)潜伏感染与复活(20秒)
4: Shedding (asymptomatic/symptomatic) (11 secs)排毒(无症状/有症状)(11秒)
5: Valtrex mode of action (16 secs)伐昔洛韦抗病毒原理(16秒)
(You may need QuickTime Player to do so, click here to download)
(可以点这个链接来下载QuickTime播放器,
http://www.apple.com/quicktime/download/ )
各片段文字描述(点图可下载动画片段):1)Herpes simplex virus (HSV) gains entry through abraded skin or mucosal tissue.单纯疱疹病毒通过破损皮肤或粘膜组织进入人体。The genital herpes virus invades the body through a vulnerable area of skin or mucous membrane.
Once inside the human cell, the viral DNA is released, tricking the cell into copying the
DNA and allowing the virus to multiply.
2)HSV is adept at penetrating the dermis and reaching the nerve pathways.单纯疱疹病毒很熟练地穿透皮肤并进入神经链路。The virus leaves the skin cell and travels up nerve pathways until it reaches the ganglion.
It can remain there in an inactive or latent state until it is triggered.
3)HSV travels nerve pathways to the nerve routes (ganglia).单纯疱疹病毒通过神经链路到达神经中枢。When triggered, commonly by stress, menstruation or fever the virus replicates and travels
back along the nerve to the skin surface.
There, it can cause blisters or other symptoms, and the virus is released during the outbreak.
4)An active phase of HSV infection can produce marked skin lesions with viral shedding.单纯疱疹病毒感染的活跃部位通过病毒性的出口来对标识皮肤造成损害。Sometimes, even without genital herpes symptoms, the virus can be released to infect a sexual partner.
5)Viral replication can be blocked by antiviral drugs that disrupt DNA.通过抗病毒药物破坏DNA来抑制病毒的复制。Valaciclovir works by selectively targeting host cells that have been invaded by the virus.
Valaciclovir blocks the replication of the virus, preventing its spread into healthy cells.